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Christopher Lee, Se Joon Woo, Duck Jin Hwang, SungChul lee; The clinical and spectral-domain optical coherence tomography findings in focal choroidal excavation. Invest. Ophthalmol. Vis. Sci. 2013;54(15):4912.
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To report the clinical and spectral-domain optical coherence tomography (SD-OCT) finding of focal choroidal excavation(FCE) in Korean population.
The medical records of 27 patients (30 eyes) with FCE were reviewed. Demography, clinical histories, and SD-OT findings were analyzed.
The mean age of patients was 51 years (range, 25-76). Seventeen (63%) patients were men. The mean refractive error was -3.7 diopters (range, +2.5 to -9.0). In 19 (63%) eyes, SD-OCT showed no separation between the outer retinal layers and the retinal pigment epithelium (RPE) (conforming type). There was a separation between the outer retina and RPE (non-conforming type) in 11 (37%) eyes. The mean largest diameter and the height of lesions were 833μm and 104μm, respectively. The mean subfoveal choroidal thickness was 275μm (range 70-571). Ten (33%) eyes were associated with central serous chorioretinopathy (CSC), nine in the affected eye and one in the unaffected fellow eye. Five (17%) eyes were associated with chorioidal neovascularization. Non-conforming type FCE was associated with greater lesion height (P=0.008) and the presence of CSC (P=0.001). There was one case of conforming type FCE with CSC, which spontaneously was converted to non-conforming type with CSC progression, and then re-converted to conforming type following intravitreal bevacizumab.
Focal choroidal excavation is a recently described idiopathic entity, which may be more common in Asian population. There appears to be an association between FCE and CSC. Choroidal neoveascularization may be associated in some patients.
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