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Eric Nudleman, Antonio Capone, Kimberly Drenser, Michael Trese; Long term outcomes of lens clarity following lens-sparing vitrectomy for retinopathy of prematurity. Invest. Ophthalmol. Vis. Sci. 2013;54(15):4946.
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This study aimed to evaluate the long term outcomes on lens status of lens-sparing vitrectomy surgery for retinopathy of prematurity (ROP) associated retinal detachments.
Retrospective review of 220 eyes (158 patients) who underwent lens-sparing vitrectomy surgery for stage 4A, stage 4B and stage 5 ROP from 1994-2012. Lens clarity was evaluated from the most recent office visit or exam under anesthesia. In addition, success rates of surgeries were calculated based on rate of re-attachment and need for additional retinal surgeries. Visual acuity, refractive outcomes, and rate of glaucoma were also evaluated.
Visually significant cataract formation was seen in 3 of 220 eyes (1.36%) following lens-sparing vitrectomy. Mean follow up was 3.2 years (range 64 days - 18 years). Forty nine eyes (22%) required lensectomy following lens-sparing vitrectomy due to progression of retinal traction and need for additional retinal surgery. Additional retinal surgeries were performed in 11% of eyes with stage 4A, 40% with stage 4B, and 82% with stage 5. Forty two eyes (19.0%) required drops to control intraocular pressure.
Here we present the largest series and the longest follow-up to date of outcomes following lens-sparing vitrectomy for ROP. We found the rate of cataract formation to be approximately one percent. Success rates for retinal re-attachement with a single surgery was approximately 89% for stage 4A, 60% for stage 4B and 18% for stage 5.
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