June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Corneal sensitivity changes following cross-linking for progressive lower stage keratoconus
Author Affiliations & Notes
  • Belquiz Nassaralla
    Cataract Cornea & Refractive Surgery, Instituto de Olhos de Goiania, Goiania, Brazil
  • Anelise Lago
    Cataract Cornea & Refractive Surgery, Instituto de Olhos de Goiania, Goiania, Brazil
  • Larissa Rossana Stival
    Cataract Cornea & Refractive Surgery, Instituto de Olhos de Goiania, Goiania, Brazil
  • Joao Nassaralla
    Retina and Vitreous, Instituto de Olhos de Goiania, Goiania, Brazil
  • Footnotes
    Commercial Relationships Belquiz Nassaralla, None; Anelise Lago, None; Larissa Rossana Stival, None; Joao Nassaralla, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 5260. doi:https://doi.org/
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      Belquiz Nassaralla, Anelise Lago, Larissa Rossana Stival, Joao Nassaralla; Corneal sensitivity changes following cross-linking for progressive lower stage keratoconus. Invest. Ophthalmol. Vis. Sci. 2013;54(15):5260. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To evaluate corneal sensitivity changes following corneal cross-linking (CXL) in patients with progressive lower stage keratoconus.

Methods: Thirty eight eyes of 19 patients (11 women, 8 men) were included in a prospective, nonrandomized clinical study. Mean patient age was 22 years (range, 18-26 years). Inclusion criteria were low stage bilateral progressive keratoconus, transparent cornea and thinnest corneal thickness ≥ 440 µm. Using the Cochet-Bonnet esthesiometer central corneal sensitivity was measured preoperatively, after 7 days, and once a month after surgery until recovery of the baseline preoperative level. Normal levels of central corneal sensitivity were considered above 40mm.

Results: Corneal sensitivity gradually returned to preoperative levels in all treated eyes. Mean central corneal sensitivity was 52.2, 24.0, 38.2, 42.4, 50.0, and 52.4 mm before surgery, at 7 days, and at 1, 2, 3 and 4 months after surgery, respectively. Normal levels of corneal sensation, but not baseline preoperative levels, were noted 2 months after surgery. Preoperative levels were observed 3 months after surgery.

Conclusions: Our results suggest that after CXL for progressive lower stage keratoconus, central corneal sensitivity is decreased for as long as 3 months.

Keywords: 482 cornea: epithelium • 574 keratoconus • 462 clinical (human) or epidemiologic studies: outcomes/complications  
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