Abstract
Purpose:
Compare thickness of corneas from eye banks with 200mOsm and 400mOsm riboflavin.
Methods:
Corneas placed in artificial chamber had pachymetry with epithelium, without epithelium and 30 minutes after application of anything (group 1-control); isosmolar (0,1% 400mOsm) riboflavin (group 2); hiposmolar (0,1% 200mOsm) riboflavin (group 3) and saline solution (group 4).
Results:
72 corneas were used; average prior pachymetry was 592μm and 548,8μm after removal of the epithelium. Group 1, 2 and 3 had decrease in thickness and group 4 had an increase. The average decrease in group 2 was 68,95μm, more than twice the average of group 3 (31,45μm).
Conclusions:
Hiposmolar riboflavin prevents the decrease in thickness when compared to isoosmolar riboflavin.
Keywords: 574 keratoconus •
479 cornea: clinical science