Abstract
Purpose:
To describe which gaps in soft contact lens (SCL) performance were addressed by refitting habitual SCL wearers with silicone hydrogel (SiHyDD) or hydrogel daily disposable (HydDD) lenses in the 1-DAY ACUVUE® TruEye® or 1-DAY ACUVUE® MOIST® Performance Overview (TEMPO) Registry (#NCT01467557).
Methods:
Self-administered questionnaires (n=598) from participants who completed Baseline, 2 Week and 4 Month questionnaires were analyzed for differences at baseline and change over time by habitual lens group (Reusable SiHy n=369, Reusable Hyd n=59, Hydrogel DD n=170). Change in Contact Lens Dry Eye Questionnaire-8 (CLDEQ-8) score, hours of comfortable wear, self-rating of ease of use and compliance with instructions for wear were tested with t-tests or Wilcoxon Signed Rank tests by habitual lens group and new lens brand.
Results:
The CLDEQ-8 score improved significantly for all treatment arms (Baseline mean ranged from 11.6±6.2 for HydDD habitual SCLs to 15.9±7.1 for Reusable Hyd) at all visits except for the Hyd to HydDD group at the 4 month visit (p<0.0004, all other comparisons). Symptoms of dryness and discomfort improved more among SiHyDD wearers compared to HydDD, but improvement in intensity of blurry vision was equivalent for the two DD lenses. Mean wearing times were unchanged but mean comfortable wearing time improved by 1.0 to 2.3 hours (p<0.02 @ 4Months all comparisons) for all groups except among former wearers of reusable Hyd or HydDD lenses that were in the HydDD treatment group (p=0.21 and 0.23 @ 4 Mo). Ease of use and compliance with instructions were rated significantly higher at Baseline by DD lens wearers compared with Reusable SCL wearers (Compliance; 86% vs. 62%, p<0.0001 and Ease 93% vs 60% Excellent/Very Good, p<0.0001) and both improved significantly after refitting only for the Former wearers of Reusable SCLs (p<0.0001).
Conclusions:
Responses from this observational, practice based study show the patient’s perspective on SCL wear after changing to these SiHyDD and HyDD lenses. The primary advantages noted were in reduction in dryness and discomfort symptoms, lengthening of comfortable wearing time and expected improvements in ease of use and compliance with instructions offered by the DD modality.
Keywords: 477 contact lens •
486 cornea: tears/tear film/dry eye