June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Struggle with Soft Contact Lens Wear Addressed by Refitting with Daily Disposable Lenses
Author Affiliations & Notes
  • Robin Chalmers
    Clinical Trial Consultant, Atlanta, GA
  • Sheila Hickson-Curran
    Clinical Trial Consultant, Atlanta, GA
  • Lisa Keay
    Clinical Trial Consultant, Atlanta, GA
  • William Gleason
    Clinical Trial Consultant, Atlanta, GA
  • Roger Albright
    Clinical Trial Consultant, Atlanta, GA
  • Footnotes
    Commercial Relationships Robin Chalmers, Alcon Research Ltd (C), Johnson & Johnson Vision Care, Inc. (F), Alcon Research Ltd (F), CooperVision Corp. (C); Sheila Hickson-Curran, Vistakon, Johnson & Johnson Vision Care, Inc. (E); Lisa Keay, None; William Gleason, Vistakon (C), Allergan (C), CooperVision (C), Semprus BioSciences (C), Vista Scientific (C), Eyetronix (C), Menicon (C), Adventus Technologies (C), Sauflon (C); Roger Albright, Johnson & Johnson Vision Care Inc. (C), CooperVision Inc. (C), Menicon Ltd. (C), Semprus Biosciences (C), VISTA Scientific, LLC (C)
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 5458. doi:https://doi.org/
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      Robin Chalmers, Sheila Hickson-Curran, Lisa Keay, William Gleason, Roger Albright; Struggle with Soft Contact Lens Wear Addressed by Refitting with Daily Disposable Lenses. Invest. Ophthalmol. Vis. Sci. 2013;54(15):5458. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To describe which gaps in soft contact lens (SCL) performance were addressed by refitting habitual SCL wearers with silicone hydrogel (SiHyDD) or hydrogel daily disposable (HydDD) lenses in the 1-DAY ACUVUE® TruEye® or 1-DAY ACUVUE® MOIST® Performance Overview (TEMPO) Registry (#NCT01467557).

Methods: Self-administered questionnaires (n=598) from participants who completed Baseline, 2 Week and 4 Month questionnaires were analyzed for differences at baseline and change over time by habitual lens group (Reusable SiHy n=369, Reusable Hyd n=59, Hydrogel DD n=170). Change in Contact Lens Dry Eye Questionnaire-8 (CLDEQ-8) score, hours of comfortable wear, self-rating of ease of use and compliance with instructions for wear were tested with t-tests or Wilcoxon Signed Rank tests by habitual lens group and new lens brand.

Results: The CLDEQ-8 score improved significantly for all treatment arms (Baseline mean ranged from 11.6±6.2 for HydDD habitual SCLs to 15.9±7.1 for Reusable Hyd) at all visits except for the Hyd to HydDD group at the 4 month visit (p<0.0004, all other comparisons). Symptoms of dryness and discomfort improved more among SiHyDD wearers compared to HydDD, but improvement in intensity of blurry vision was equivalent for the two DD lenses. Mean wearing times were unchanged but mean comfortable wearing time improved by 1.0 to 2.3 hours (p<0.02 @ 4Months all comparisons) for all groups except among former wearers of reusable Hyd or HydDD lenses that were in the HydDD treatment group (p=0.21 and 0.23 @ 4 Mo). Ease of use and compliance with instructions were rated significantly higher at Baseline by DD lens wearers compared with Reusable SCL wearers (Compliance; 86% vs. 62%, p<0.0001 and Ease 93% vs 60% Excellent/Very Good, p<0.0001) and both improved significantly after refitting only for the Former wearers of Reusable SCLs (p<0.0001).

Conclusions: Responses from this observational, practice based study show the patient’s perspective on SCL wear after changing to these SiHyDD and HyDD lenses. The primary advantages noted were in reduction in dryness and discomfort symptoms, lengthening of comfortable wearing time and expected improvements in ease of use and compliance with instructions offered by the DD modality.

Keywords: 477 contact lens • 486 cornea: tears/tear film/dry eye  
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