June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Visual Performance and Optical Quality with New Silicone-hydrogel Soft Contact Lenses for Keratoconus
Author Affiliations & Notes
  • Asaki Suzaki
    Applied Visual Science, Osaka University Graduate School of Medicine, Suita, Japan
  • Naoyuki Maeda
    Ophthalmology, Osaka University Graduate School of Medicine, Suita, Japan
  • Mutsumi Fuchihata
    Ophthalmology, Osaka University Graduate School of Medicine, Suita, Japan
  • Shizuka Koh
    Ophthalmology, Osaka University Graduate School of Medicine, Suita, Japan
  • Kohji Nishida
    Ophthalmology, Osaka University Graduate School of Medicine, Suita, Japan
  • Takashi Fujikado
    Applied Visual Science, Osaka University Graduate School of Medicine, Suita, Japan
  • Footnotes
    Commercial Relationships Asaki Suzaki, Menicon Co., Ltd. (E); Naoyuki Maeda, Topcon (F), Santen (R), Otsuka (R), Oculus (R), HOYA (R); Mutsumi Fuchihata, None; Shizuka Koh, Santen, Inc. (R), Johnson & Johnson (R), Topcon (R), Otsuka Pharmaceutical Co. (R); Kohji Nishida, Alcon (C), Alcon (F), HOYA (F), Senju (F), Pfizer (F), Santen (F), Osaka University (P); Takashi Fujikado, Nidek (P)
  • Footnotes
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Investigative Ophthalmology & Visual Science June 2013, Vol.54, 5487. doi:https://doi.org/
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      Asaki Suzaki, Naoyuki Maeda, Mutsumi Fuchihata, Shizuka Koh, Kohji Nishida, Takashi Fujikado; Visual Performance and Optical Quality with New Silicone-hydrogel Soft Contact Lenses for Keratoconus. Invest. Ophthalmol. Vis. Sci. 2013;54(15):5487. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To study the visual performances of a novel silicone-hydrogel soft contact lens (Si-SCL), which was designed to correct a refractive vertical asymmetry in keratoconic eyes.

Methods: Fifty eyes of 37 subjects with mild keratoconus were recruited for the study. Measurements included corneal anterior optical coherence tomography (SS-1000, Tomey), wavefront aberrometry (KR-1W, Topcon), subjective refraction, visual acuity (VA), visual clarity with visual analog scale (VAS). Study lenses were made by molding method and were consisted of 6 types, in which asymmetrical power distribution (2D, 4D, 6D, 8D, 10D, 12D) was created to correct vertical irregular astigmatism. Based on the topography and aberrometry data, the type of lenses was selected and fitted to the subjects. Evaluation of the on-eye performance of the lens was carried out, including wavefront aberrometry (4mm pupil, root mean square), over-refraction, VA, visual clarity with VAS.

Results: Monocular visual performance with a Si-SCL improved from -0.03±0.13 to -0.08±0.08 LogMAR in VA (p<0.01), from 61.2±20.7 to 73.8±18.5 VAS scores in vision clarity (p<0.01). Vertical coma-aberration and total higher-order aberrations (HOAs) were reduced {naked eyes: -0.49±0.36 µm in vertical coma and 0.66±0.39 µm in HOAs; with the lenses: -0.35±0.38 µm in vertical coma (p<0.05) and 0.61±0.39 µm in HOAs (p<0.05)}.

Conclusions: A novel Si-SCL designed to correct refractive vertical asymmetry has improved the monocular visual performance as well as the degree of vertical coma in eyes with keratoconus.

Keywords: 477 contact lens • 574 keratoconus • 626 aberrations  
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