June 2013
Volume 54, Issue 15
ARVO Annual Meeting Abstract  |   June 2013
Assessment of Intervisit IOP Control in Eyes with Advanced Glaucoma
Author Affiliations & Notes
  • Priya Patel
    New Jersey Medical School, Newark, NJ
  • Nicole Pritz
    New Jersey Medical School, Newark, NJ
  • Robert Fechtner
    New Jersey Medical School, Newark, NJ
  • Albert Khouri
    New Jersey Medical School, Newark, NJ
  • Footnotes
    Commercial Relationships Priya Patel, None; Nicole Pritz, None; Robert Fechtner, None; Albert Khouri, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 5634. doi:
  • Views
  • Share
  • Tools
    • Alerts
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Priya Patel, Nicole Pritz, Robert Fechtner, Albert Khouri; Assessment of Intervisit IOP Control in Eyes with Advanced Glaucoma. Invest. Ophthalmol. Vis. Sci. 2013;54(15):5634.

      Download citation file:

      © ARVO (1962-2015); The Authors (2016-present)

  • Supplements

The Advanced Glaucoma Intervention Study (AGIS) provided evidence more than a decade ago that low intraocular pressure (IOP) was associated with reduced progression of visual field defects. The aim of this study was to evaluate the extent of intervisit control of IOP with current treatments of patients with advanced glaucoma.


Medical records of consecutive patients with a diagnosis of advanced primary open angle glaucoma (POAG) at New Jersey Medical School between 06/2012 and 11/2012 were reviewed. Inclusion: POAG with documented cup-to-disc ratio ≥ 0.8 and visual field abnormalities in both hemifields and/or loss within 5° of fixation in at least one hemifield as tested with standard automated perimetry, >9 office visits. Exclusion: Glaucoma other than POAG, mild to moderate POAG, <9 office visits. Data on IOP, ocular medications, lens status, and ophthalmic surgeries (incisional and laser) were collected. IOP was categorized into one of four groups (Excellent <14, Good 14-17.5, Fair 18-21, Poor >21mmHg; consistent with AGIS). Effect of lens status and glaucoma surgery was analyzed. Percentages, means, paired t-tests, and chi-square analyses were used.


493 time points were collected for 50 eyes (28 patients). Mean age was 65 years (range: 46 to 88 years). The numbers of time points that fell within the various categories were: Excellent 173/493 (35%), Good 179/493 (36%), Fair 75/493 (15%), Poor 66/493 (13%). When further grouped into time points < or ≥ 18 mmHg, glaucoma surgery and lower mean number of medications were statistically significantly higher in time points with IOP <18 mmHg. The number of time points < 18 mmHg was higher for pseudophakic eyes, but this did not reach statistical significance (Table 1).


In eyes with advanced POAG, IOP control below 18 mmHg was achieved in about 70% of office visits, and was more often seen in eyes after glaucoma surgery. Rigorous IOP control remains a challenge in advanced POAG more than a decade after AGIS recommendations.

Keywords: 568 intraocular pressure • 462 clinical (human) or epidemiologic studies: outcomes/complications  

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.