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Cristobal Couto, Maria de las Mercedes Frick, Bernardo Schlaen, Erika Miolet Hurtado Jallaza, Matilde Lopez; Chronic anterior uveitis in paediatric patients. Invest. Ophthalmol. Vis. Sci. 2013;54(15):5665.
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To describe clinical features and visual prognosis of chronic anterior uveitis in paediatric patients.
The medical records of 35 paediatric patients who met criteria for chronic anterior uveitis (SUN) were reviewed to identify clinical features, complications, visual outcome and treatment between 1996 and 2012 at the University of Buenos Aires
There were 35 patients, 21 (60%) girls, mean age 7,4 years ( r: 2-15 ) and mean follow up 79,2 months ( r: 12-192). Out of 35, 26 (74,2%) presented bilateral uveitis. ANA was positive in 19 (54,2%) patients while arthritis was found in 18 (51,4%). Metotrexate was given in 25 (71,4%) patients. Fourteen patients (40%) were treated with biologics agents: 11 with Adalimumab, 3 with Etanercept, 1 with Infliximab and 1 with Rituximab. Final visual acuity better than 20/40 was found in 49 out of 61 (80%) eyes. Most common complications were band keratopathy in 20 eyes, cataract in 16 eyes and posterior sinechiaes in 13 eyes. Facoemulsification with IOL was performed in 10 eyes. Regresion of uveitis after a mean time of treatment of 8 years was achieved in 6 patients.
In our series, chronic anterior uveitis was related to Juvenile Idiopathic Arthritis only in half of patients. Therefore, not all chronic anterior uveitis in children are associated with JIA. Regarding treatment 40% of our patients had to receive biologic agents to improve the inflammation.
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