June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Refractive Error And Cause Of Vision Impairment Among Children In A Low Vision Service
Author Affiliations & Notes
  • Dawn DeCarlo
    Ophthalmology, Univ of Alabama at Birmingham, Birmingham, AL
  • Gerald McGwin
    Ophthalmology, Univ of Alabama at Birmingham, Birmingham, AL
    Epidemiology, University of Alabama at Birmingham, Birmingham, AL
  • Elizabeth Forte
    Ophthalmology, Univ of Alabama at Birmingham, Birmingham, AL
  • Liyan Gao
    Ophthalmology, Univ of Alabama at Birmingham, Birmingham, AL
  • Cynthia Owsley
    Ophthalmology, Univ of Alabama at Birmingham, Birmingham, AL
  • Footnotes
    Commercial Relationships Dawn DeCarlo, None; Gerald McGwin, None; Elizabeth Forte, None; Liyan Gao, None; Cynthia Owsley, Genentech (F), Patent Licensed to: MacuLogix (P), Allergan (R)
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 5727. doi:
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    • Get Citation

      Dawn DeCarlo, Gerald McGwin, Elizabeth Forte, Liyan Gao, Cynthia Owsley; Refractive Error And Cause Of Vision Impairment Among Children In A Low Vision Service. Invest. Ophthalmol. Vis. Sci. 2013;54(15):5727.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose
 

To examine the causes of vision impairment (VI) among children referred for vision rehabilitation and to determine the relationship between refractive error and diagnosis.

 
Methods
 

Charts of all children seen for vision rehabilitation in a university-based low vision rehabilitation service between October 2005 and September 2012 were retrospectively reviewed. Children ages 2 to 18 whose records contained: date of birth, primary ocular diagnosis, visual acuity and refractive error were included. For children with more than one visit during that time period, only the baseline visit was used in this analysis.

 
Results
 

440 charts were abstracted and 377 met inclusion criteria. The most common etiology for vision impairment was albinism (17.2%) followed by optic atrophy (12.7%), retinal degeneration (9.8%), optic nerve hypoplasia (8.8%) and cortical vision impairment (5.8%). There was a wide range of refractive error (spherical equivalent (SE) OD -26.50 to +18.50 and OS -25.25 to +19.25). The SE was not normally distributed (Kolmogorov-Smirnov test, p<0.010). The mean SE was OD: -0.90 ±6.0 and OS: -0.70±5.9 and the median SE refractive error was plano OD and OS. Although the mean refractive error was small, 69.5% of right and 69.6% of left eyes had SE refractive error greater than ±1D (see figures 1 & 2). The range of astigmatism was from 0 to -6.00D OD and 0 to -8.00D OS. Astigmatism was common with 53% of right and 50% of left eyes having astigmatism ≥1D. There were no refractive trends associated with ocular diagnosis with the exceptions of the obvious diagnoses of high myopia and aphakia.

 
Conclusions
 

The diagnosis related to VI in this U.S. study is different than that found in other developing and developed countries as well as from that reported previously from a school for the blind in the same state. A multi-center study is necessary to better understand the epidemiology of childhood vision impairment. Children with VI in this sample have significant refractive error, with a leptokurtic distribution. Some studies have reported a normal distribution of refractive error among children with VI, suggesting that vision impairment interferes with emmetropization. Here, there is evidence for emmetropization in the presence of VI, however there are large tails to the distribution suggesting the mechanism for emmetropization may be less precise.

 
 
Fig. 1: SE distribution for OD
 
Fig. 1: SE distribution for OD
 
 
Fig. 2: SE distribution for OS
 
Fig. 2: SE distribution for OS
 
Keywords: 584 low vision • 676 refraction • 511 emmetropization  
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