June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Risk factors for development of full thickness macular holes following pars plana vitrectomy for myopic foveoschisis
Author Affiliations & Notes
  • Yasushi Ikuno
    Department of Ophthalmology, Osaka Univ Medical School, Suita, Japan
  • Xinxiao Gao
    Department of Ophthalmology, Osaka Univ Medical School, Suita, Japan
  • Satoko Fujimoto
    Department of Ophthalmology, Osaka Univ Medical School, Suita, Japan
  • Kohji Nishida
    Department of Ophthalmology, Osaka Univ Medical School, Suita, Japan
  • Footnotes
    Commercial Relationships Yasushi Ikuno, Topcon (F), TOMEY (F); Xinxiao Gao, None; Satoko Fujimoto, None; Kohji Nishida, Alcon (C), Alcon (F), HOYA (F), Senju (F), Pfizer (F), Santen (F), Osaka University (P)
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 5782. doi:
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    • Get Citation

      Yasushi Ikuno, Xinxiao Gao, Satoko Fujimoto, Kohji Nishida; Risk factors for development of full thickness macular holes following pars plana vitrectomy for myopic foveoschisis. Invest. Ophthalmol. Vis. Sci. 2013;54(15):5782.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To explore the risk factors of secondary full thickness macular holes following pars plana vitrectomy with inner limiting membrane (ILM) peeling for myopic foveoschisis

Methods: The medical records of all patients who underwent pars plana vitrectomy with ILM peeling for myopic foveoschisis with or without retinal detachment from January 2002 to June 2012 were retrospectively reviewed. The factors for developing of postoperative full thickness macular holes were investigated.

Results: Forty-two eyes with myopic foveoschisis but without macular hole before surgery were included in this study and 8 cases (19.0%) of them were identified to develop a postoperative full thickness macular hole by optical coherence tomography (OCT) during the follow-up period. No significant association of age (P =.369), axial length (P =.113), visual acuity (P =.859), status of fovea (P =.331), posterior staphyloma (P =1.000) or chorioretinal atrophy (P =0.837) were found between patients with and without secondary macular holes. Among the characteristics on OCT images, the percentage of eyes with the inner segment/outer segment junction (IS/OS) defect was significantly higher in the patients with macular hole than in those without macular hole (P =.013, Fisher exact test). IS/OS defect (P =0.018) was the only significant risk factor for development of secondary macular holes by logistic regression analysis.

Conclusions: Development of secondary macular holes may occur in myopic foveoschisis following pars plana vitrectomy with ILM peeling. Preoperative IS/OS defect can be a risk factor.

Keywords: 762 vitreoretinal surgery • 605 myopia • 586 macular holes  
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