June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Detection of Fundus Abnormalities in Diabetic Retinopathy using Spectal Domain OCT versus Mydriatic Color Fundus Imaging
Author Affiliations & Notes
  • Qing Shao
    Ophthalmology, Charité-Universitätsmedizin, Berlin, Germany
  • Yanling Ouyang
    Ophthalmology, Charité-Universitätsmedizin, Berlin, Germany
    Ophthalmology, Doheny Eye Institute - USC, Los Angeles, CA
  • Florian Heussen
    Ophthalmology, Charité-Universitätsmedizin, Berlin, Germany
    Ophthalmology, Doheny Eye Institute - USC, Los Angeles, CA
  • Alexander Walsh
    Ophthalmology, Doheny Eye Institute - USC, Los Angeles, CA
  • Antonia Joussen
    Ophthalmology, Charité-Universitätsmedizin, Berlin, Germany
  • Srinivas Sadda
    Ophthalmology, Doheny Eye Institute - USC, Los Angeles, CA
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 5827. doi:
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    • Get Citation

      Qing Shao, Yanling Ouyang, Florian Heussen, Alexander Walsh, Antonia Joussen, Srinivas Sadda; Detection of Fundus Abnormalities in Diabetic Retinopathy using Spectal Domain OCT versus Mydriatic Color Fundus Imaging. Invest. Ophthalmol. Vis. Sci. 2013;54(15):5827.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose
 

To determine the sensitivity for detection of retinal abnormalities using volume Spectral Domain OCT versus single field fundus imaging in eyes of patients with diabetes.

 
Methods
 

Images from consecutive patients in a retina clinic undergoing simultaneous volume spectral domain OCT scanning (512x128) and single field, foveal-centered mydriatic 45 degree color fundus imaging with a 3D-OCT-1000 (Topcon Corp, Tokyo, Japan) over a 29 month period were retrospectively collected. Findings for each modality (Table 1) were graded independently by two graders as being present, questionable or absent. Findings from both modalities were combined to form the gold standard for comparison for each modality.

 
Results
 

A total of 312 volume OCT scans and fundus images from 312 eyes of 167 patients were included in this study. 234 eyes were clinically diagnosed with diabetic retinopathy (DR) with varying severities. In this cohort (Table 1), OCT was more sensitive than color photos for most features, in particular the detection of cystoid macular edema and vitreous hemorrhage. Vascular abnormalities such as venous beading were not detectable by OCT.

 
Conclusions
 

In this study, OCT was more sensitive than a color fundus photograph for detection of many abnormalities in eyes of patients with diabetes. The prospect of OCT as a potential adjunctive tool in screening applications warrants further study.

  
Keywords: 499 diabetic retinopathy • 552 imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound)  
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