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Byung Ro Lee, Yong Un Shin, Sang hyup Lee; Steroid-associated central serous chorioretinopathy, multidisciplinary imaging. Invest. Ophthalmol. Vis. Sci. 2013;54(15):5864.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate characteristics findings of steroid-associated central serous chorioretinopathy (CSC) using various imaging techniques
31 eyes of 16 patients were enrolled retrospectively. All patients underwent comprehensive ophthalmologic examination and various imaging exams such as spectral-domain optical coherence tomography (SD-OCT), retro-mode imaging, fundus autofluorescence (FAF), fluorescein angiography (FA) and indocyanine green angiography (IA). We investigated characteristic clinical features of steroid-associated CSC presented by various imaging techniques.
Nine were males and seven were females. All patients had a history of taking oral steroid medication. The causes of steroid medication were kidney transplantation (5 patients), rheumatologic diseases (8 patients) and others (3 patients). The dose and duration of steroid administrations were in the range of 5mg ~ 60mg per day and 1 week ~ 20 years respectively. At first visit, 8 patients showed bilateral serous detachment (SRD) and 8 patients showed unilateral SRD but FA or IA showed abnormal findings in the fellow eye. In SD-OCT, most of eyes (29 eyes) showed early or late chronic CSC patterns, while 6 eyes showed acute CSC pattern. In FA, bilateral multifocal or diffuse leakage patterns were mostly observed. In IA, bilateral choroidal hyperpermeability were also observed in most eyes. The FAF showed various patterns according to the chronicity of the disease.
We described distinct imaging characteristics of steroid-associated CSC distinguished from idiopathic CSC. Steroid-associated CSC can be also classified into acute or chronic CSC according to imaging patterns. Our imaging description may help to determine the chronicity of the disease and treatment option of steroid-associated CSC.
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