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taneto tomiyasu, Shuichiro Hirahara, Munenori Yoshida, Miho Nozaki, Yuichiro Ogura; Ultra-wide field fluorescein angiography in patients with diabetic retinopathy. Invest. Ophthalmol. Vis. Sci. 2013;54(15):5872. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
The ultra-wide field scanning laser ophthalmoscope (Optos®200Tx, Optos ,Scotland, UK) provides retinal images of 200 degrees in a single capture which covers more than 80% of the retina. Fluorescein angiography (FA) with Optos®200Tx is useful to visualize the microcirculations of peripheral retina. It allows to evaluate peripheral pathology more precisely than the conventional fundus photography. The purpose of this study is to evaluate the FA findings of the eyes in diabetic retinopathy patients by using ultra-wide field FA (UWFA).
The UWFA was performed on 154 eyes of 77 patients with diabetic retinopathy (62 male, 15 female, average of age; 60.2±11.8 years). We divided the fundus into three zones, the posterior pole, the mid-periphery, and the far-periphery. Capillary non-perfusion areas in each zone were evaluated.
One hundred thirty eyes (86%) exhibited capillary non-perfusion areas. The ischemic area was found in the posterior pole (60 eyes, 46%), the mid-peripheral zone (113 eyes, 87%), and the far-peripheral zone (84 eyes, 65%), respectively. Twenty-one eyes (16%) were found to have the capillary non-perfusion area only in the mid-periphery, while 10 eyes (8%) showed the non-perfusion area only in the far-periphery without any evidences of non-perfusion in the posterior pole and the mid-periphery. Fifty nine eyes (38%) exhibited neovascularization. They were found in the posterior pole (26 eyes, 44% ), the mid-peripheral zone (53 eyes, 90%), and the far-peripheral zone (4 eyes, 7%), respectively.
The UWFA revealed the microcirculatory disturbance in the peripheral retina of diabetic patients which was not evident by the conventional fundus photography. The UWFA was useful for evaluating the status of diabetic retinopathy.
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