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Peter Hovland; Clinical utility of SD-OCT -Enhanced Depth Imaging in Evaluation of Retinal and Choroidal Tumors of the Human Eye. Invest. Ophthalmol. Vis. Sci. 2013;54(15):5897.
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© ARVO (1962-2015); The Authors (2016-present)
To present illustrative examples of clinical cases in which the use of the Heidelberg Spectralis instrument created uniquely useful images which allow for the precise determination of diagnosis, anatomic localization and dimension, and local tissue effects of intraocular tumors.
A non-randomized series of patients presenting to an ocular oncology clinic were selected for testing with the Heidelberg Spectralis instrument on the EDI-OCT setting. Correlation with clinical history was applied to the interpretation of the images. EDI-OCT images were obtained of CHRPE, choroidal nevus, treatment naive choroidal melanoma, treated choroidal melanoma (status-post brachytherapy, diode laser, intravitreal bevacizumab and/or argon laser), and metastatic choroidal and retinal lesions.
In an analysis of over 50 patients, the EDI-OCT could precisely determine the depth of the lesions when the maximal depth did not exceed 2 mm. For choroidal lesions, overlying tissue changes of the retina could be described in terms of presence or absence of subretinal fluid, photoreceptor changes, retinal edema or degeneration, and RPE abnormalities. Changes in these tissue elements can be followed over time as a means of surveillance to monitor for evidence of neoplasm, or response to treatment.
The EDI-OCT provides an extremely useful adjunct to standard techniques in the work-up and surveillance of ocular oncology patients, and especially so for the monitoring of smaller suspicious lesions.
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