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Hee-Bae Ahn, Hyemi Jung, Mee sook Roh, Won Yeol Ryu, Yoon Hyung Kwon; The Effects of Temperature - sensitive Guardix SG® in Adhesiolysis of Experimentally Induced Lid Adhesion Rabbits. Invest. Ophthalmol. Vis. Sci. 2013;54(15):6381.
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To evaluate the effects of Guardix SG® following adhesiolysis for preventing postoperative adhesion.
The rabbits were categorized into two groups ; adhesiolysis alone in left eyelids (control group), adhesiolysis with Guardix SG® in right eyelids (Guardix SG® group). The experimental lid adhesion was achieved by blepharoplasty with NaOH. Then adhesiolysis was done with or without Guardix SG®. The degree of adhesion was evaluated microscopically.
Within 2 weeks after surgery, the shape of the eyelids had recovered completely in both groups. The Guardix SG® group showed less inflammation and fibrosis than the control group, microscopically.
Guardix SG® is an effective adjunctive method for reducing postoperative adhesion.
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