Morphological Iris Analysis Using OCT Visante in Tamsulosin Users

Abstract

 

Purpose

 

The purpose of this study is to compare, evaluate and analyse iris morphology using OCT Visante in patients with benign hyperplasic prostate currently in treatment with tamsulosin versus patients with the same age, without prostatic pathology and without any kind of treatment

 

Methods

 

Study Design: Comparative, observational and transversal. Iris measurements were taken with OCT Visante divided in thirds at 0 - 180 degrees and 90 - 270 degrees in patients previously instilled with topical pilocarpin 2%, three times every ten minuts previous to the imaging study. Inclusion Criteria: Patients older than 55 years using tamsulosin without any other pathology besides benign hiperplasic prostate. Exclusion Criteria: Age < 55 years, less than 3 months of treatment with tamsulosin, in treatment with another alpha antagonist and those who did not wish to participate in this study. Elimination Criteria: Death, non compliance with treatment or with appointments.

 

Results

 

60 eyes were studied, 30 for the study group and 30 for the control group. The findings show an increased thickness at the iris sphincter (p<0.05) in the sudy group versus control group. The dilator muscle also showed a marked thinning in the study group versus de control group although this different did not show any statistical significance.

 

Conclusions

 

The morphological changes in the iris that were found in this study can be closely related to the transsurgical findings in patients that show floppy iris syndrome. At the time of this study there were no other studies comparing patients taking tamsulosin versus control group via OCT Visante measurements. The findings in the study group should be taken to account tu fully prepare the cataract surgeon for the possible transoperatory complications related to these morphological changes.

 

 

Keywords: 571 iris • 550 imaging/image analysis: clinical • 421 anterior segment