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Juan Carlos Ondategui Parra, Lorena Mateos-Pena, Joan Martinez-Roda, Montserrat Arjona; Measurement of the intraocular scattering in cataractous patients, using different instruments and parameters. Comparative study. Invest. Ophthalmol. Vis. Sci. 2013;54(15):851.
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© ARVO (1962-2015); The Authors (2016-present)
To perform clinical measurements of intraocular scattering in cataractous patients by means of different available commercial instruments that have become common in clinical practice
Intraocular scattered light was measured by means of two different available commercial instruments: the CQuant system (Oculus), which provides an absolute intraocular scattering value (log(s)) (Van der Berg et al Ophthal. Physiol Opt. 2009), and the OQAS (Visiometrics), which uses the Objective Scatter Index (OSI) parameter (Artal el al. Plos One 2011) obtained from the double-pass retinal image. 78 cataractous eyes of 52 patients were included in the study (37 right eyes, and 41 left eyes), 41 female and 37 male with a mean ± SD in age of 68.24 ± 8.3 years (range: 47 to 85 years), spherical manifest refraction ranged from -8.00 to +5.75D and the cylinder from 0.00 to 3.00D, best spectacle-corrected visual acuity in the logMAR scale of 0.17±0.27 (1.25 to -0.20). The grade and type of cataract was: 24 eyes of nuclear cataract (30.4%), 27 of mixed nuclear (34.2%), 9 eyes of cortical (11.4%) and 18 of posterior subcapsular (24.1%). CSF was also measured using CSV-1000 (Vector Vision
Considering all types of cataract, the Pearson correlation between log(s) and OSI is statistically significant (r=0.339 and p=0.002). For high degree of cataract and high OSI values (OSI>8) inconsistencies appear (normally low values of log(s)). Removing this values a better correlation (r=0.559 and p<0.001) is obtained. The correlation between log(s) and OSI values separate in nuclear cataract group(r=0.654 and p=0.001) and mixed nuclear cataract group (r=0.707 p<0.001), is statistically significant. There is no statistically significant Pearson correlation for both cortical cataracts group (r=0.524 and p=0.286), and for posterior subcapsular cataract group (r=0.359 and p=0.144). Pearson correlation r between CS (3, 6, 12, and 18 c/deg), LogMAR log(s) and OSI is statistically significant in more cases with OSI than with log (s)
C-Quant and OQAS are good predicting methods of the gradation of different types of cataracts in the clinical practice, although the OSI parameter has shown more statistically significant results. Future work will be focused on a larger number of patients with cortical and subcapsular cataracts.
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