June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Correlating visual function and size of area opacified by retrodots based on retro-illumination photography
Author Affiliations & Notes
  • Hiroshi Sasaki
    Department of Ophthalmology, Kanazawa Medical University, Uchinada, Japan
  • Norihiro Mita
    Department of Ophthalmology, Kanazawa Medical University, Uchinada, Japan
  • Natsuko Hatsusaka
    Department of Ophthalmology, Kanazawa Medical University, Uchinada, Japan
  • Eri Shibuya
    Department of Ophthalmology, Kanazawa Medical University, Uchinada, Japan
  • Mai Sasaki
    Department of Ophthalmology, Kanazawa Medical University, Uchinada, Japan
  • mai takahashi
    Department of Ophthalmology, Kanazawa Medical University, Uchinada, Japan
  • Yoriko Takahashi
    Department of Ophthalmology, Kanazawa Medical University, Uchinada, Japan
  • Hiromi Osada
    Department of Ophthalmology, Kanazawa Medical University, Uchinada, Japan
  • Kazuyuki Sasaki
    Department of Ophthalmology, Kanazawa Medical University, Uchinada, Japan
  • Eri Kubo
    Department of Ophthalmology, Kanazawa Medical University, Uchinada, Japan
  • Footnotes
    Commercial Relationships Hiroshi Sasaki, None; Norihiro Mita, None; Natsuko Hatsusaka, None; Eri Shibuya, None; Mai Sasaki, None; mai takahashi, None; Yoriko Takahashi, None; Hiromi Osada, None; Kazuyuki Sasaki, None; Eri Kubo, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 864. doi:https://doi.org/
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      Hiroshi Sasaki, Norihiro Mita, Natsuko Hatsusaka, Eri Shibuya, Mai Sasaki, mai takahashi, Yoriko Takahashi, Hiromi Osada, Kazuyuki Sasaki, Eri Kubo; Correlating visual function and size of area opacified by retrodots based on retro-illumination photography. Invest. Ophthalmol. Vis. Sci. 2013;54(15):864. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To consider the relationship between area opacified by retrodots (RD) and visual function (best corrected visual acuity (BCVA), retinal image contrast (RIC), and high-order aberration).

Methods: Subjects comprised 140 right eyes with RD (average age 69.6±7.1 yrs) excluding other types of cataract including three main types (nuclear, cortical and posterior subcapsular cataract), water clefts and lens opacities which may affect vision, and non-cataractous eye disease, among participants of Monzen Eye Study (Monzen, Wajima City, Ishikawa, Japan) from 2006 to 2012. The area opacified by RD within the 3 mm diameter area of the pupil center (under maximal mydriasis by tropicamide) was measured with anterior eye segment analysis system (EAS-100, Nidek). RIC with the 3 mm diameter pupil and total high-order aberrations (corneal, internal, ocular) with the 4 mm diameter pupil were measured by PSF analyzer (PSF-1000, Topcon) and wavefront analyzer (KR9000PW, Topcon), respectively. RIC was measure for low, middle and high frequency with optotypes 0.081logMAR, 0.423logMAR and 0.008logMAR.

Results: Size of area opacified by RD was positively correlated with BCVA (logMAR) (p<0.05). BCVA was 0logMAR and 0.2logMAR for areas of RD 10% and 25%, respectively. There was a negative correlation between size of area opacified by RD and RIC for all three optotypes (p<0.05). RIC deteriorated by 10% as RD area increased by 10%. There was no significant correlation between area of RD and corneal, internal and ocular total high-order aberrations.

Conclusions: Within the area of 3 mm diameter of the pupil center, over 10% opacification by RD reduces VA to less than 0logMAR and RIC by 10%. However, a 10% opacification does not affect high-order aberration.

Keywords: 445 cataract • 754 visual acuity • 459 clinical (human) or epidemiologic studies: biostatistics/epidemiology methodology  
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