February 1972
Volume 11, Issue 2
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Articles  |   February 1972
In Vivo Measurements of Oxygen Tension in the Cornea, Aqueous Humor, and Anterior Lens of the Open Eye
Author Affiliations
  • MARCUS KWAN
    Department of Surgery, Room HSE-839, University of California School of Medicine, San Francisco, Calif.; Albert Einstein College of Medicine, Bronx, N. Y. 10461
  • JUHA NIINIKOSKI
    Department of Surgery, Room HSE-839, University of California School of Medicine, San Francisco, Calif.; Department of Surgery, University of Turku, Turku, Finland
  • THOMAS K. HUNT
    Department of Surgery, Room HSE-839, University of California School of Medicine, San Francisco, Calif.
Investigative Ophthalmology & Visual Science February 1972, Vol.11, 108-114. doi:
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      MARCUS KWAN, JUHA NIINIKOSKI, THOMAS K. HUNT; In Vivo Measurements of Oxygen Tension in the Cornea, Aqueous Humor, and Anterior Lens of the Open Eye. Invest. Ophthalmol. Vis. Sci. 1972;11(2):108-114.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Measurements of oxygen profiles across the cornea, aqueous humor, and anterior lens differed from previously calculated values. The aqueous humor oxygen tension in paiticular also differed from previously measured values, being approximately 20 mm. Hg higher. Reasons for these differences are discussed. The tissue oxygen gradients measured confirm the high QO2 of lenticular and corneal epithelium and corneal endothelium. The steady state PO2 in stroma and anterior nucleus reflects the low QO2 of these tissues. The profiles reaffirm the atmospheric source of oxygen to the corneal epithelium and stroma of the open eye and suggest that the corneal endothelium and anterior lens are completely nourished by the aqueous humor oxygen.

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