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GEORGE E. MARAK, RAMON L. FONT, MERRILL C. JOHNSON, F. PAUL ALEPA; Lymphocyte-Stimulating Activity of Ocular Tissues in Sympathetic Ophthalmia. Invest. Ophthalmol. Vis. Sci. 1971;10(10):770-774.
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Blastogenic activity of ocular tissue extracts was elicited in lymphocyte cultures from peripheral blood of two of four patients with sympathetic ophthalmia. Retinal pigment epithelium, retina, and lens were mitogenic, while choroidal antigen was usually inactive. There was no evidence of cellular hypersensitivity to ocular tissue in several other forms of uveitis. The problems in interpreting these observations are discussed.
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