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ATSUSHI KANAI, FRANK M. POLACK; Ultramicroscopic Changes in the Corneal Graft Stroma During Early Rejection. Invest. Ophthalmol. Vis. Sci. 1971;10(6):415-423.
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Early rejection of corneal stroma of penetrating homografts demonstrates various degrees of keratocyte degeneration. The altered cells are almost always in contact with small round or oval-shaped lymphocytes. Stromal changes are more pronounced in areas adjacent to epithelial or endothelial rejection. Lymphocytes, plasma cells, macrophages, and immunoblasts are present in large numbers at the host stroma or around limbal vessels where they seem to accumulate and replicate.
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