January 1973
Volume 12, Issue 1
Articles  |   January 1973
Effects of prolonged exposure of rabbit retina to low-intensity light
Author Affiliations
  • Theodore Lawwill
    Department of Ophthalmology, University of Louisville, School of Medicine Louisville, Ky.
Investigative Ophthalmology & Visual Science January 1973, Vol.12, 45-51. doi:
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      Theodore Lawwill; Effects of prolonged exposure of rabbit retina to low-intensity light. Invest. Ophthalmol. Vis. Sci. 1973;12(1):45-51.

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      © ARVO (1962-2015); The Authors (2016-present)

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Rabbit's eyes were exposed to various levels of measured illumination for four hours. Two sources with different spectral content were compared for their ability to cause retinal damage. The damage was assessed by ophthalmoscopy, electroretinography, and histology. The threshold for minimal detectable damage with a broad-spectrum source occurred around 0.045 watt per square centimeter. A monochromatic source at 514.5 nm. produced damage at one fifth this power level. When the two sources were matched by electroretinography for visual efficiency in the rabbit, the thresholds for damage were approximately equal. This shows that the visible portion of the spectrum is primarily responsible for retinal damage under these conditions


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