April 1975
Volume 14, Issue 4
Articles  |   April 1975
Conjunctival goblet cell density in normal subjects and in dry eye syndromes.
Investigative Ophthalmology & Visual Science April 1975, Vol.14, 299-302. doi:
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      R A Ralph; Conjunctival goblet cell density in normal subjects and in dry eye syndromes.. Invest. Ophthalmol. Vis. Sci. 1975;14(4):299-302.

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      © ARVO (1962-2015); The Authors (2016-present)

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Serial sections prepared from biopsies of the deep tarsal portion of the inferior nasal conjunctival fornix in normal subjects and in patients with various dry eye syndromes were analyzed with respect to the goblet cell densities. When compared to normal subjects, individuals with keratitis sicca, Stevens-Johnson syndrome, ocular pemphigoid, and acute alkali burn all demonstrated progressively lower goblet cell densities per millimeter of epithelial surface. These disease entities can, therefore, be considered goblet cell-deficient syndromes.


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