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G A Peyman, P Homer, R Kasbeer, J Vlchek; Full-thickness eye wall biopsy. II. In primates.. Invest. Ophthalmol. Vis. Sci. 1975;14(7):565-567.
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We devised a technique to perform an intact full-thickness eye wall biopsy in primates. An eye basket is sutured to the eye wall for stabilization. Trephines demarcate and incise a 4 to 7 mm. circumferential area of sclera; diathermy deepens the incision until perforation is achieved. The biopsy specimen is removed and immediately fixed for histologic evaluation, and the eye wall defect is covered by a 7 mm. scleral homograft. Our results showed that histologically excellent biopsies can be obtained with minimal damage to the eye.
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