December 1976
Volume 15, Issue 12
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Articles  |   December 1976
Immunofluorescent studies on the trabecular meshwork in open-angle glaucoma.
Investigative Ophthalmology & Visual Science December 1976, Vol.15, 1014-1017. doi:https://doi.org/
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      M B Shields, R C McCoy, J D Shelburne; Immunofluorescent studies on the trabecular meshwork in open-angle glaucoma.. Invest. Ophthalmol. Vis. Sci. 1976;15(12):1014-1017. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

The trabecular meshwork of eyes with open-angle glaucoma has been demonstrated to have an increase in gamma globulin and plasma cells, raising the question of an immunogenic mechanism in this disorder. In the present study, however, immunofluorescence assays on the trabecular meshwork of eyes with open-angle glaucoma were negative for specific immunoglobulins and for complement components that would result specifically from an antigen-antibody reaction. The study fails to provide any evidence in support of an immunogenic mechanism in open-angle glaucoma.

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