April 1976
Volume 15, Issue 4
Articles  |   April 1976
Corneal membrane water permeability as a function of temperature.
Investigative Ophthalmology & Visual Science April 1976, Vol.15, 304-307. doi:https://doi.org/
  • Views
  • PDF
  • Share
  • Tools
    • Alerts
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      K Green, S J Downs; Corneal membrane water permeability as a function of temperature.. Invest. Ophthalmol. Vis. Sci. 1976;15(4):304-307. doi: https://doi.org/.

      Download citation file:

      © ARVO (1962-2015); The Authors (2016-present)

  • Supplements
This content is PDF only. Please click on the PDF icon to access.

Osmotically driven water flow across the corneal epithelium and endothelium has been measured as a function of temperature. For both membranes deviations from a single straight-line relationship are found in a logarithmic plot of hydraulic conductivity against 1/T. Both membranes show a high (14 to 16 kcal per mole) apparent activation energy at temperatures between 23 degrees C. and 5 degrees C. At higher temperatures, between 23 degrees C. and 37 degrees C., the apparent activation energy falls to 5.7 and 9.3 kcal per mole for the epithelium and endothelium, respectively. The low value for the apparent activation energy for water crossing the epithelium and endothelium at normal corneal temperatures presumably reflects water passage through water-filled channels.


This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.