October 1975
Volume 14, Issue 10
Articles  |   October 1975
Ascorbic acid stimulates chloride transport in the amphibian cornea.
Investigative Ophthalmology & Visual Science October 1975, Vol.14, 763-766. doi:
  • Views
  • PDF
  • Share
  • Tools
    • Alerts
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      W N Scott, D F Cooperstein; Ascorbic acid stimulates chloride transport in the amphibian cornea.. Invest. Ophthalmol. Vis. Sci. 1975;14(10):763-766.

      Download citation file:

      © ARVO (1962-2015); The Authors (2016-present)

  • Supplements
This content is PDF only. Please click on the PDF icon to access.

The cornea of the toad, Bufo marinus, actively transports chloride from the endothelial to the epithelial surface. This transport process has been related to the maintenance of the normal transparency of the cornea. Ion transport, as evidenced by the short-circuit current (SCC), is markedly stimulated by physiologic concentrations of ascorbic acid. Measurement of the unidirectional fluxes of 36Cl and 22Na shows that the increase in SCC is due primarily to a stimulation of the active transport of chloride.


This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.