June 1977
Volume 16, Issue 6
Free
Articles  |   June 1977
Extraocular muscle fibers: ultrastructural identification of iontophoretically labeled fibers contracting in response to succinylcholine.
Investigative Ophthalmology & Visual Science June 1977, Vol.16, 561-565. doi:
  • Views
  • PDF
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      P Bach-y-Rita, G Lennerstrand, J Alvarado, K Nichols, G McHolm; Extraocular muscle fibers: ultrastructural identification of iontophoretically labeled fibers contracting in response to succinylcholine.. Invest. Ophthalmol. Vis. Sci. 1977;16(6):561-565.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
This content is PDF only. Please click on the PDF icon to access.
Abstract

Cat extraocular muscle fibers (from the superior rectus or inferior oblique) were penetrated in vivo with Procion red-filled glass microelectrodes. When stable penetrations were obtained, succinylcholine (Sch), 8 to 20 microng, was injected into the femoral vein. In some fibers, a depolarization-repolarization response was obtained with the same time course (2 min.) as the total muscle contraction. The depolarizing fibers were labeled iontophoretically. The ultrastructural characteristics of five depolarizing fibers and three control (nondepolarizing) fibers were then studied. The fibers that did not depolarize to Sch had the characteristics of singly innervated cells, whereas those sensitive to Sch had morphological characteristics of multi-innervated fibers.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×