March 1980
Volume 19, Issue 3
Articles  |   March 1980
Altering the course of cataracts in diabetic rats.
Investigative Ophthalmology & Visual Science March 1980, Vol.19, 313-315. doi:
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      S Fukushi, L O Merola, J H Kinoshita; Altering the course of cataracts in diabetic rats.. Invest. Ophthalmol. Vis. Sci. 1980;19(3):313-315.

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      © ARVO (1962-2015); The Authors (2016-present)

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A potent new aldose reductase (AR) inhibitor was effective in preventing cataractous changes in diabetic rats. Untreated diabetic rats developed early lens changes by 3 weeks and dense nuclear opacities by 6 to 9 weeks. In contrast, diabetic rats treated with the AR inhibitor showed no lens changes during the 5-month period of the experiment.


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