Purchase this article with an account.
S Fukushi, L O Merola, J H Kinoshita; Altering the course of cataracts in diabetic rats.. Invest. Ophthalmol. Vis. Sci. 1980;19(3):313-315.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
A potent new aldose reductase (AR) inhibitor was effective in preventing cataractous changes in diabetic rats. Untreated diabetic rats developed early lens changes by 3 weeks and dense nuclear opacities by 6 to 9 weeks. In contrast, diabetic rats treated with the AR inhibitor showed no lens changes during the 5-month period of the experiment.
This PDF is available to Subscribers Only