December 1980
Volume 19, Issue 12
Articles  |   December 1980
Actin filaments in retinal pericytes and endothelial cells.
Investigative Ophthalmology & Visual Science December 1980, Vol.19, 1433-1441. doi:
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      I H Wallow, B Burnside; Actin filaments in retinal pericytes and endothelial cells.. Invest. Ophthalmol. Vis. Sci. 1980;19(12):1433-1441.

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      © ARVO (1962-2015); The Authors (2016-present)

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The contractile protein actin was identified within retinal capillary pericytes and endothelial cells. In capillary cross-sections, circumferential pericyte processes showed numerous parallel bundles of actin filaments forming a cap over the adjacent endothelial cells. The latter contained few actin filaments but a considerable number of intermediate filaments. Pericytes and endothelial cells communicated via gaps in the adluminal basal lamina. These special anatomic relationships are interpreted as evidence for a contractile role of retinal capillary pericytes and against a contractile role of retinal capillary endothelial cells


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