March 1980
Volume 19, Issue 3
Articles  |   March 1980
Effect of flurbiprofen on herpes simplex keratitis in rabbits.
Investigative Ophthalmology & Visual Science March 1980, Vol.19, 267-270. doi:
  • Views
  • PDF
  • Share
  • Tools
    • Alerts
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      M D Trousdale, E C Dunkel, A B Nesburn; Effect of flurbiprofen on herpes simplex keratitis in rabbits.. Invest. Ophthalmol. Vis. Sci. 1980;19(3):267-270.

      Download citation file:

      © ARVO (1962-2015); The Authors (2016-present)

  • Supplements
This content is PDF only. Please click on the PDF icon to access.

The rabbit ocular model was used to determine if flurbiprofen, a new nonsteroidal antiinflammatory agent, caused exacerbation of herpes simplex virus (HSV) infection. Acute ocular HSV infections treated with flurbiprofen (0.1%) or dexamethasone (0.1%) drops four times a day for 10 days were similar in severity and duration as measured by corneal lesions, conjunctivitis, and corneal clouding. Eyes receiving placebo healed more rapidly than eyes treated with either anti-inflammatory drug. This preliminary study suggests that flurbiprofen appears to be comparable with dexamethasone in clinical exacerbation of acute ocular HSV infection.


This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.