December 1981
Volume 21, Issue 6
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Articles  |   December 1981
Aerobic responses of the cornea to ophthalmic preservatives, measured in vivo.
Investigative Ophthalmology & Visual Science December 1981, Vol.21, 842-845. doi:
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      G D Burton, R M Hill; Aerobic responses of the cornea to ophthalmic preservatives, measured in vivo.. Invest. Ophthalmol. Vis. Sci. 1981;21(6):842-845.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

A micropolarographic system was used to measure the effects of several concentrations of benzalkonium chloride and thimerosal on oxygen uptake by the cornea. Although the threshold of 0.01% found for benzalkonium chloride generally agreed with other criteria (e.g., clinical and histologic) in the current literature, the threshold for thimerosal was somewhat higher, 1.0%, indicating a substantially greater aerobic activity tolerance of the cornea to initial direct exposures of that agent then to benzalkonium chloride.

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