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L H Liu, D M Albert, H G Dohlman, N Chuo; Metastasis in a rabbit choroidal melanoma model.. Invest. Ophthalmol. Vis. Sci. 1982;22(1):115-118. doi: https://doi.org/.
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A substrain of Greene hamster melanoma adapted to grow in the choroid of the rabbit eye is shown to have the tendency to metastasize. Twenty-one normal rabbits were studied for the effects of vascular inoculation of a tumor cell suspension prepared from this choroidal melanoma, and two rabbits were used for long-term observation of the natural untreated course of the choroidal melanoma. In both groups, metastases to the liver, lung, kidney, and other organs were demonstrated.
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