January 1982
Volume 22, Issue 1
Articles  |   January 1982
Metastasis in a rabbit choroidal melanoma model.
Investigative Ophthalmology & Visual Science January 1982, Vol.22, 115-118. doi:
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      L H Liu, D M Albert, H G Dohlman, N Chuo; Metastasis in a rabbit choroidal melanoma model.. Invest. Ophthalmol. Vis. Sci. 1982;22(1):115-118.

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      © ARVO (1962-2015); The Authors (2016-present)

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A substrain of Greene hamster melanoma adapted to grow in the choroid of the rabbit eye is shown to have the tendency to metastasize. Twenty-one normal rabbits were studied for the effects of vascular inoculation of a tumor cell suspension prepared from this choroidal melanoma, and two rabbits were used for long-term observation of the natural untreated course of the choroidal melanoma. In both groups, metastases to the liver, lung, kidney, and other organs were demonstrated.


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