June 1984
Volume 25, Issue 6
Articles  |   June 1984
The relation of retinal sensitivity and rhodopsin in developing rat retina.
Investigative Ophthalmology & Visual Science June 1984, Vol.25, 647-651. doi:
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      A B Fulton, B N Baker; The relation of retinal sensitivity and rhodopsin in developing rat retina.. Invest. Ophthalmol. Vis. Sci. 1984;25(6):647-651.

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      © ARVO (1962-2015); The Authors (2016-present)

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The authors have studied the relations of rhodopsin and retinal sensitivity in developing albino rats, (1) in the dark-adapted state and (2) after exposure to light that bleaches greater than 90% of rhodopsin. Developmental increases in dark-adapted b-wave sensitivity and rhodopsin content were related directly as has been reported previously for rhodopsin and PIII sensitivity of other developing retinas. During dark-adaptation, infant rat log a-wave and log b-wave sensitivities and adults' log b-wave sensitivity were related linearly to the proportion of rhodopsin present. The authors suspect that the sensitivity-rhodopsin relations of infant rat retina are determined mainly by photoreceptor processes. Thus, the infant rat provides a model for investigation of mechanisms underlying both (1) the direct relation of sensitivity and rhodopsin and (2) the log sensitivity-rhodopsin relation.


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