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K Takatsuji, Y Sato, S Iizuka, H Nakatani, A Nakamura; Animal model of closed angle glaucoma in albino mutant quails.. Invest. Ophthalmol. Vis. Sci. 1986;27(3):396-400.
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© ARVO (1962-2015); The Authors (2016-present)
The intraocular pressure of imperfect albino mutant quails with a sex-linked recessive gene was measured by using a cannulating method, and morphological changes of the iridocorneal angle were observed with a gonioprism. Albino mutant quails were characterized by an elevated intraocular pressure and lens enlargement at 6 mo after hatching. Initially the iridocorneal angle opened and eventually closed. The usefulness of the closed angle glaucoma as an animal model system for human diseases was discussed.
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