June 1988
Volume 29, Issue 6
Free
Articles  |   June 1988
Angiotensin-converting enzyme in bovine, feline, and human ocular tissues.
Author Affiliations
  • G Ferrari-Dileo
    Bascom Palmer Eye Institute, Miami, FL 33101.
  • J W Ryan
    Bascom Palmer Eye Institute, Miami, FL 33101.
  • E J Rockwood
    Bascom Palmer Eye Institute, Miami, FL 33101.
  • E B Davis
    Bascom Palmer Eye Institute, Miami, FL 33101.
  • D R Anderson
    Bascom Palmer Eye Institute, Miami, FL 33101.
Investigative Ophthalmology & Visual Science June 1988, Vol.29, 876-881. doi:
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    • Get Citation

      G Ferrari-Dileo, J W Ryan, E J Rockwood, E B Davis, D R Anderson; Angiotensin-converting enzyme in bovine, feline, and human ocular tissues.. Invest. Ophthalmol. Vis. Sci. 1988;29(6):876-881.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Angiotensin-converting enzyme was shown to be present in retinal vessels and neural retina of feline, bovine, and human eyes. It was also demonstrated in the other ocular tissues of feline eyes, in especially high concentration in the highly vascular uveal layer. Its role in the physiology of ocular blood flow and neurophysiology is uncertain, especially in the retina where circulating angiotensin and bradykinin are confined to the intravascular space by the blood-retina barrier, and sufficient data are not available to describe these peptides as transmitters or modulator molecules in the retina.

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