August 1963
Volume 2, Issue 4
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Articles  |   August 1963
The Development of Glaucoma in Rabbits
Author Affiliations
  • ALLAN E. KOLKER
    Department of Ophthalmology and the Oscar Johnson Institute, Washington University School of Medicine, St. Louis, Mo.
  • ROBERT A. MOSES
    Department of Ophthalmology and the Oscar Johnson Institute, Washington University School of Medicine, St. Louis, Mo.
  • MARGUERITE A. CONSTANT
    Department of Ophthalmology and the Oscar Johnson Institute, Washington University School of Medicine, St. Louis, Mo.
  • BERNARD BECKER
    Department of Ophthalmology and the Oscar Johnson Institute, Washington University School of Medicine, St. Louis, Mo.
Investigative Ophthalmology & Visual Science August 1963, Vol.2, 316-321. doi:
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      ALLAN E. KOLKER, ROBERT A. MOSES, MARGUERITE A. CONSTANT, BERNARD BECKER; The Development of Glaucoma in Rabbits. Invest. Ophthalmol. Vis. Sci. 1963;2(4):316-321.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

In an attempt to study the development of glaucoma in rabbits, animals with establishedglaucoma and buphthalmos were bred, and their offspring followed with tonography at monthly intervals. Findings indicated that: (A) The animals developing glaucoma, as determined by a corneal diameter of 17 mm. or more at 1 year of age, had elevated intraocular pressures at 5 to 6 months of age, and impaired outflow facilities as early as 3 months of age. (B) Animals with corneal diameters of 15 mm. or less at 1 year showed no pressure elevations, and had much higher outflow facilities throughout the first year of life.

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