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ALLAN E. KOLKER, ROBERT A. MOSES, MARGUERITE A. CONSTANT, BERNARD BECKER; The Development of Glaucoma in Rabbits. Invest. Ophthalmol. Vis. Sci. 1963;2(4):316-321.
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© ARVO (1962-2015); The Authors (2016-present)
In an attempt to study the development of glaucoma in rabbits, animals with establishedglaucoma and buphthalmos were bred, and their offspring followed with tonography at monthly intervals. Findings indicated that: (A) The animals developing glaucoma, as determined by a corneal diameter of 17 mm. or more at 1 year of age, had elevated intraocular pressures at 5 to 6 months of age, and impaired outflow facilities as early as 3 months of age. (B) Animals with corneal diameters of 15 mm. or less at 1 year showed no pressure elevations, and had much higher outflow facilities throughout the first year of life.
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