December 1989
Volume 30, Issue 12
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Articles  |   December 1989
Uptake of tritiated thymidine in mitochondria of the retina.
Author Affiliations
  • B J Woodford
    Department of Anatomy, University of Southern California School of Medicine, Los Angeles.
  • J C Blanks
    Department of Anatomy, University of Southern California School of Medicine, Los Angeles.
Investigative Ophthalmology & Visual Science December 1989, Vol.30, 2528-2532. doi:
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      B J Woodford, J C Blanks; Uptake of tritiated thymidine in mitochondria of the retina.. Invest. Ophthalmol. Vis. Sci. 1989;30(12):2528-2532.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Light microscopic autoradiography with 3H-thymidine was used as a probe for DNA synthesis on the retinas of the guinea pig, rabbit, and monkey. Relatively heavy labeling was found in the ganglion cell and inner nuclear layers as well as in the photoreceptor inner segments in the guinea pig and monkey. Electron microscopic autoradiography demonstrated that in the ganglion cells and photoreceptor inner segments in the monkey, 89% of silver grains, representing thymidine uptake, were on or near the mitochondria.

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