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FRANK M. POLACK, GEORGE K. SMELSER, JEANETTE ROSE; The Fate of Cells in Heterologous Corneal Transplants. Invest. Ophthalmol. Vis. Sci. 1963;2(4):355-360. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
The fate of intralamellar corneal heterografts was investigated by radioautography. The corneal connective tissue cells of rabbit eyes were labeled with tritiated thytnidine and. grafted intralamellarly into cat corneas. In 8 out of 9 clear transplants, radioautographs demonstrated that the donor cells had persisted in grafts varying in age from 2 to 10 months. Donor cells were not found in 4 opaque grafts. In additional experiments the possibility of host cells being labeled by radioactive material from dead donor cells was investigated. There was no radioauto graphic evidence of reutilization of labeled nuclear debris.
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