May 1986
Volume 27, Issue 5
Articles  |   May 1986
A monoclonal antibody that binds to cones.
Investigative Ophthalmology & Visual Science May 1986, Vol.27, 831-836. doi:
  • Views
  • PDF
  • Share
  • Tools
    • Alerts
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      V Lemmon; A monoclonal antibody that binds to cones.. Invest. Ophthalmol. Vis. Sci. 1986;27(5):831-836.

      Download citation file:

      © ARVO (1962-2015); The Authors (2016-present)

  • Supplements
This content is PDF only. Please click on the PDF icon to access.

A monoclonal antibody that binds to cones has been produced. This antibody, 50-1B11, binds to the outer segments of cones in rhesus monkeys. Immunohistochemical experiments indicate that 50-1B11 binds to a subset of photoreceptors, probably cones, in all vertebrate species tested thus far, including man. In vitro experiments on chicken retina indicate that the antigen is intracellular and associated with the plasma membrane, while electronmicroscopic-immunohistochemical studies demonstrate that the antigen is contained in the lamellae of the outer segments of rhesus cones.


This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.