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K Yamaguchi, V P Gaur, R W Young, A J Sweatt; Cellular retinoic acid-binding protein in rat lacrimal gland.. Invest. Ophthalmol. Vis. Sci. 1991;32(13):3273-3276.
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We employed a monoclonal antibody to cellular retinoic acid-binding protein (CRABP) to assess the presence and localization of this retinoid-binding protein in the lacrimal gland of the rat. Immunoblots of extracts of rat lacrimal gland showed specific immunostaining of lacrimal CRABP in the region 14-16 kDa. Sections of rat lacrimal glands that were stained with anti-CRABP antibodies showed reaction product in the cytoplasm of the acinar cells. Retinoic acid may play a role in maintaining the proper function of lacrimal gland cells.
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