February 1989
Volume 30, Issue 2
Free
Articles  |   February 1989
Optic disc cupping: four year follow-up from the WESDR.
Author Affiliations
  • B E Klein
    Department of Ophthalmology, University of Wisconsin Medical School, Madison.
  • S E Moss
    Department of Ophthalmology, University of Wisconsin Medical School, Madison.
  • Y L Magli
    Department of Ophthalmology, University of Wisconsin Medical School, Madison.
  • R Klein
    Department of Ophthalmology, University of Wisconsin Medical School, Madison.
  • C Hoyer
    Department of Ophthalmology, University of Wisconsin Medical School, Madison.
  • J Johnson
    Department of Ophthalmology, University of Wisconsin Medical School, Madison.
Investigative Ophthalmology & Visual Science February 1989, Vol.30, 310-315. doi:
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    • Get Citation

      B E Klein, S E Moss, Y L Magli, R Klein, C Hoyer, J Johnson; Optic disc cupping: four year follow-up from the WESDR.. Invest. Ophthalmol. Vis. Sci. 1989;30(2):310-315.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Change in optic disc cupping was evaluated in a 4-year follow-up of a well defined cohort of people with diabetes mellitus. Cup-to-disc ratios were computed for both vertical and horizontal diameters of each eye at the baseline and 4-year follow-up examinations. Graders were masked as to the identity of participants and to the dates of the photographs. Increases of at least 0.1 between baseline and follow-up were used as clinically significant change in the ratios. None of the following factors at baseline were consistent predictors of such a change: intraocular pressure, age, duration of diabetes, hypertension or severity of diabetic retinopathy. People who developed proliferative retinopathy by the follow-up examination were not more likely to have such an increase in ratio at the follow-up. We conclude that clinically significant increases in cup-to-disc ratio cannot be consistently predicted in people with diabetes from the risk factors evaluated with the grading system used in this study.

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