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Abstract
Flat preparations of the central lens epithelium in 181 human donor eyes, 120 male, 61 female, were used to determine epithelial cell density. Donor age ranged from 13 to 91 years. A similar linear age-dependent decrease of cell density was found in both sexes. In addition, the epithelial cell density was significantly higher in females. The age-adjusted mean cell density in males was 5008.6 cells/mm2, in females 5780.6 cells/mm2. A similar sex difference had been found before in lens epithelium of human cataracts. The cause and significance of this observation are unknown.