September 1992
Volume 33, Issue 10
Free
Articles  |   September 1992
A comparison of photopic and scotopic electroretinographic changes in early diabetic retinopathy.
Author Affiliations
  • K Holopigian
    Department of Ophthalmology, New York University Medical Center, New York.
  • W Seiple
    Department of Ophthalmology, New York University Medical Center, New York.
  • M Lorenzo
    Department of Ophthalmology, New York University Medical Center, New York.
  • R Carr
    Department of Ophthalmology, New York University Medical Center, New York.
Investigative Ophthalmology & Visual Science September 1992, Vol.33, 2773-2780. doi:
  • Views
  • PDF
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      K Holopigian, W Seiple, M Lorenzo, R Carr; A comparison of photopic and scotopic electroretinographic changes in early diabetic retinopathy.. Invest. Ophthalmol. Vis. Sci. 1992;33(10):2773-2780.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Previous studies of early diabetic retinopathy have shown that oscillatory potential (OP) amplitudes are reduced in many diabetic patients. OP amplitude is believed to be a more sensitive indicator of the development of future retinopathy than b-wave amplitude of the scotopic electroretinogram (ERG). Because OPs measured to a bright white flash reflect both rod and cone system activity, it is important to compare OP amplitudes to photopic ERG measures as well as scotopic measures in early diabetic retinopathy. In this study, OPs and ERG responses were measured under photopic and scotopic conditions in a group of diabetic patients. Although OPs were reduced in amplitude in the diabetic group, several other parameters of the scotopic and photopic b-waves were impaired. The results indicate that b-wave activity may indicate retinal changes in early diabetic retinopathy in the same manner as the OPs.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×