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V C Greenstein, A Shapiro, Q Zaidi, D C Hood; Psychophysical evidence for post-receptoral sensitivity loss in diabetics.. Invest. Ophthalmol. Vis. Sci. 1992;33(10):2781-2790.
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Although numerous reports show that the sensitivity of the S cone system is decreased in diabetic patients, few studies have been directed toward identifying the possible sites of the sensitivity loss. In this study, a psychophysical technique was used to test hypotheses about sites of S cone system sensitivity loss in a group of patients with early diabetic retinopathy. A model of the S cone system was assumed and the experimental conditions were chosen to distinguish between explanations for S cone sensitivity loss at the receptor level from explanations for loss at a post-receptoral level. Within the context of the model, the data were consistent with S cone system sensitivity loss occurring at a post-receptoral level.
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