September 1992
Volume 33, Issue 10
Free
Articles  |   September 1992
Psychophysical evidence for post-receptoral sensitivity loss in diabetics.
Author Affiliations
  • V C Greenstein
    Department of Ophthalmology, New York University Medical Center, NY 10016.
  • A Shapiro
    Department of Ophthalmology, New York University Medical Center, NY 10016.
  • Q Zaidi
    Department of Ophthalmology, New York University Medical Center, NY 10016.
  • D C Hood
    Department of Ophthalmology, New York University Medical Center, NY 10016.
Investigative Ophthalmology & Visual Science September 1992, Vol.33, 2781-2790. doi:
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    • Get Citation

      V C Greenstein, A Shapiro, Q Zaidi, D C Hood; Psychophysical evidence for post-receptoral sensitivity loss in diabetics.. Invest. Ophthalmol. Vis. Sci. 1992;33(10):2781-2790.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Although numerous reports show that the sensitivity of the S cone system is decreased in diabetic patients, few studies have been directed toward identifying the possible sites of the sensitivity loss. In this study, a psychophysical technique was used to test hypotheses about sites of S cone system sensitivity loss in a group of patients with early diabetic retinopathy. A model of the S cone system was assumed and the experimental conditions were chosen to distinguish between explanations for S cone sensitivity loss at the receptor level from explanations for loss at a post-receptoral level. Within the context of the model, the data were consistent with S cone system sensitivity loss occurring at a post-receptoral level.

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