July 1990
Volume 31, Issue 7
Free
Articles  |   July 1990
Effect of levodopa on the human luminance electroretinogram.
Author Affiliations
  • I Gottlob
    I. University Eye Clinic, Vienna, Austria.
  • H Weghaupt
    I. University Eye Clinic, Vienna, Austria.
  • C Vass
    I. University Eye Clinic, Vienna, Austria.
Investigative Ophthalmology & Visual Science July 1990, Vol.31, 1252-1258. doi:
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      I Gottlob, H Weghaupt, C Vass; Effect of levodopa on the human luminance electroretinogram.. Invest. Ophthalmol. Vis. Sci. 1990;31(7):1252-1258.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Scotopic and photopic electroretinograms (ERGs) were recorded in 12 healthy volunteers before and 90 and 180 min after administration of levodopa. After 90 min the drug significantly increased the scotopic ERG b-wave amplitude and implicit time. The dark-adapted oscillatory potentials (OPs) were selectively affected, while no changes were observed in the photopic ERG. Levodopa had no effect on the ERG after 180 min drug applications. As a control, the experimental procedure was repeated without drug administration, and no changes were observed.

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