April 1989
Volume 30, Issue 4
Free
Articles  |   April 1989
Breakdown of the blood--aqueous barrier in the rabbit eye by infrared radiation.
Author Affiliations
  • R T Kurnik
    Department of Ophthalmology, Washington University School of Medicine, St. Louis, Missouri.
  • R M Burde
    Department of Ophthalmology, Washington University School of Medicine, St. Louis, Missouri.
  • B Becker
    Department of Ophthalmology, Washington University School of Medicine, St. Louis, Missouri.
Investigative Ophthalmology & Visual Science April 1989, Vol.30, 717-722. doi:
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      R T Kurnik, R M Burde, B Becker; Breakdown of the blood--aqueous barrier in the rabbit eye by infrared radiation.. Invest. Ophthalmol. Vis. Sci. 1989;30(4):717-722.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Breakdown of the blood-aqueous barrier was produced by infrared radiation (IR) at a heat flux from 24 to 44 J/cm2 in pigmented, but not in albino rabbits. Blood-aqueous barrier breakdown was inhibited by indomethacin and ketamine/xylazine anesthesia mixtures, but not by [D-Trp2,D-Pro7,9]-substance P. The degree of blood-aqueous barrier breakdown could be controlled by IR flux. Two models for accurate determination of the heat flux are presented.

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