April 1992
Volume 33, Issue 5
Free
Articles  |   April 1992
An experimental model of ectropion uveae and iris neovascularization in the cat.
Author Affiliations
  • L M Hjelmeland
    Department of Ophthalmology, University of California, Davis.
  • M W Stewart
    Department of Ophthalmology, University of California, Davis.
  • J Li
    Department of Ophthalmology, University of California, Davis.
  • C A Toth
    Department of Ophthalmology, University of California, Davis.
  • M S Burns
    Department of Ophthalmology, University of California, Davis.
  • M B Landers, 3rd
    Department of Ophthalmology, University of California, Davis.
Investigative Ophthalmology & Visual Science April 1992, Vol.33, 1796-1803. doi:
  • Views
  • PDF
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      L M Hjelmeland, M W Stewart, J Li, C A Toth, M S Burns, M B Landers; An experimental model of ectropion uveae and iris neovascularization in the cat.. Invest. Ophthalmol. Vis. Sci. 1992;33(5):1796-1803.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Neovascularization of the iris (NVI) is one of the most frequently studied intraocular vascular proliferations in animal models. Ectropion uveae has not been a consistent finding in these studies. In this study, a surgical model of ectropion uveae and iris neovascularization was developed that involved lensectomy, vitrectomy, bipolar cautery and transection of all three principal branch veins in the cat eye. Twelve of 14 eyes that received this procedure developed postoperative retinal detachments with a clinical picture of hemorrhagic retinopathy. These eyes progressed to a clinical picture of NVI within 1-7 wk. Eight eyes developed ectropion uveae for as much as 300 degrees. At the light microscopic level, a fibrovascular membrane was apparent on the anterior iris stroma in 9 of 14 eyes and further involved the angle in six eyes.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×