July 1993
Volume 34, Issue 8
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Articles  |   July 1993
The human S-cone electroretinogram and its variation among subjects with and without L and M-cone function.
Author Affiliations
  • P Gouras
    Edward S. Harkness Eye Institute, Columbia University, New York, New York.
  • C J MacKay
    Edward S. Harkness Eye Institute, Columbia University, New York, New York.
  • S Yamamoto
    Edward S. Harkness Eye Institute, Columbia University, New York, New York.
Investigative Ophthalmology & Visual Science July 1993, Vol.34, 2437-2442. doi:
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    • Get Citation

      P Gouras, C J MacKay, S Yamamoto; The human S-cone electroretinogram and its variation among subjects with and without L and M-cone function.. Invest. Ophthalmol. Vis. Sci. 1993;34(8):2437-2442.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

PURPOSE: To examine the S-cone ERG in subjects with and without L and M-cone function. METHODS: Ganzfeld spectral flashes in the presence of strong Ganzfeld adapting fields are used to elicit S-cone ERGs. RESULTS: The S-cone ERG b-wave ranges from 0.2 to 4 mV in amplitude and 38-45 msec in implicit time. There is a progressive decrease in amplitude with age. The response is similar in subjects with or without L and M cone function. CONCLUSION: The S-cone ERG is detectable in subjects of all ages, but intersubject variability limits its diagnostic usefulness. The S-cone ERG is slightly later than but does not appear to be obviously influenced by the L and M-cone ERG.

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